Facilities ● MRI
Metabolic Imaging

Maastricht University Medical Centre has a distinct technology platform for non-invasive imaging of ectopic fat mass, brown adipose tissue and for analysis of human energy metabolism. Using proton magnetic resonance spectroscopy (1H-MRS) researchers within NUTRIM showed that a high fat diet increases fat deposition in the liver. Using MRI muscle cross-sectional area and fat deposition can be characterized.

Energy metabolism is studied using phosphor magnetic resonance spectroscopy (31P-MRS). The ATP content can be measured in different tissues (for example liver, muscle and heart). Using this methodology, multidisciplinary research by the departments of Human Biology, Movement Sciences and Radiology elegantly showed positive effects of an exercise program on skeletal muscle metabolism of patients with diabetes.

Brown adipose tissue is detected during cold exposure in a climate controlled chamber using FDG-PET. This technique combines anatomical imaging (CT) and glucose uptake to a fusion. Maastricht researchers were one of the first to detect brown adipose tissue in humans and its response to weight loss in obese subjects.